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 Temazepam
Temazepam (marketed under brand names Normison, Temtabs, Euhypnos, Restoril, Remestan, Tenox, Temaze and Norkotral) is an intermediate-acting 3-hydroxy benzodiazepine. It is generally prescribed for the short-term treatment of sleeplessness in patients who have difficulty maintaining sleep. In addition, temazepam has anxiolytic (anti-anxiety), anticonvulsant, and skeletal muscle relaxant properties.
Systematic (IUPAC) name
7-Chloro-1,3-dihydro-
3-hydroxy-1-methyl-5-phenyl-
1,4-benzodiazepin-2-one
Identifiers
CAS number 846-50-4
ATC code N05CD07
PubChem 5391
DrugBank APRD00676
ChemSpider 5198
Chemical data
Formula C16H13ClN2O2
Mol. mass 300.7 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability 96%
Metabolism Hepatic
Half life 8–20 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat. C(AU) X(US)
Legal status Prescription Only (S4) (AU) Schedule IV (CA) ? (UK) Schedule IV (US) IV (International)
Routes Therapeutic: Oral
Recreational Abuse: Intravenous (IV), Intramuscular (IM), Insufflated, Sprinkled in ethanol, smoked
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